thz2

Item no.	V5014-100mg
Manufacturer	InvivoChem LLC
CASRN	1604810-84-5
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V5014CAS #:1604810-84-5Purity >=98% Description: THZ2, a THZ1 analog, is a novel, potent and selective CDK7 inhibitor with an IC50 of 13.9 nM. THZ2 has the potential for treating triple-negative breast cancer (TNBC) and is able to overcome the instability issue of THZ1 in vivo. References: Cell. 2015 Sep 24; 163(1):174-186.
	Name: THZ2 CAS#: 1604810-84-5 Chemical Formula: C31H28ClN7O2 Exact Mass: 565.1993 Molecular Weight: 566.06 Elemental Analysis: C, 65.78; H, 4.99; Cl, 6.26; N, 17.32; O, 5.65
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: THZ2; THZ 2; THZ-2. IUPAC/Chemical Name: N-[3-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]phenyl]-3-[[(E)-4-(dimethylamino)but-2-enoyl]amino]benzamide InChi Key: FONRCZUZCHXWBD-VGOFMYFVSA-N InChi Code: InChI=1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6-11-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-13-4-3-12-24(25)27/h3-14, 16-19, 33H, 15H2, 1-2H3, (H, 35, 40)(H, 36, 41)(H, 34, 37, 38)/b14-7+ SMILES Code: O=C(NC1=CC=CC(NC2=NC=C(Cl)C(C3=CNC4=C3C=CC=C4)=N2)=C1)C5=CC=CC(NC(/C=C/CN(C)C)=O)=C5

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Amount: 100mg

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