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pi3kmtor-inhibitor-2

pi3kmtor-inhibitor-2

Item no.	V4988-250mg
Manufacturer	InvivoChem LLC
CASRN	1848242-58-9
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4988CAS #:1848242-58-9Purity >=98% Description: PI3K/mTOR Inhibitor-2 is a novel and potent dual pan-PI3K/mTOR inhibitor with antitumor activity and with IC50 values of 3.4/34/16/1 nM for PI3Kalpha/PI3Kbeta/PI3Kdelta/PI3Kgamma and 4.7 nM for mTOR. PI3K/mTOR Inhibitor-2 exhibited high enzyme activity against PI3K and mTOR, potent suppression of Akt and p70s6k phosphorylation in cell assays, and good pharmacokinetic profile. Furthermore, PI3K/mTOR Inhibitor-2 demonstrated in vivo efficacy in a PC-3M tumor xenograft model. References: ACS Med Chem Lett. 2018 Feb 27; 9(3):256-261.
	Molecular Weight?478.86 Formula?C??H??ClF?N?O?S CAS No.?1848242-58-9 SMILES? FC1=CC(F)=C(S(=O)(NC2=CC(C(C=C3)=CN4C3=NC=C(Cl)C4=O)=CN=C2OC)=O)C=C1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	PI3K/mTOR Inhibitor-2

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250mg

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Delivery expected until 9/6/2024

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