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nsc-42834

nsc-42834

Item no.	V4974-100mg
Manufacturer	InvivoChem LLC
CASRN	195371-52-9
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4974CAS #:195371-52-9Purity >=98% Description: NSC 42834 (also known as JAK2 Inhibitor V) is a novel, potent and specific inhibitor of JAK2 which inhibits JAK2-V617F and JAK2-WT autophosphorylation in a dose-dependent manner with IC50 values between 10 and 30 uM. It was not cytotoxic to cells at concentrations that inhibited kinase activity. References: Mol Cancer Ther 2008; 7(8):2308-18.; Current Oncology Reports. 2009, 11(2): 117-124.
	Name: NSC-42834 CAS#: 195371-52-9 Chemical Formula: C23H24N2O Exact Mass: 344.1889 Molecular Weight: 344.458 Elemental Analysis: C, 80.20; H, 7.02; N, 8.13; O, 4.64 O
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: NSC 42834; NSC-42834; NSC42834; Janus-Associated Kinase Inhibitor V; Z3. JAK2 Inhibitor V. IUPAC/Chemical Name: 2-methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one InChi Key: SETYDCSRABYHSW-UHFFFAOYSA-N InChi Code: InChI=1S/C23H24N2O/c1-23(15-13-20-11-5-7-17-24-20, 16-14-21-12-6-8-18-25-21)22(26)19-9-3-2-4-10-19/h2-12, 17-18H, 13-16H2, 1H3 SMILES Code: O=C(C(CCC1=CC=CC=N1)(CCC2=NC=CC=C2)C)C3=CC=CC=C3

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Amount: 100mg

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Delivery expected until 9/6/2024

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