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Description: ML-792 (ML792) is a novel, potent and specific small ubiquitin-like modifier (SUMO)-activating enzyme (SAE) inhibitor. ML-792 is a selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays with IC50s of 3 and 11 nM, respectively, compared with NAE/NEDD8 and UAE/ubiquitin (IC50s of 32 uM and > 100 uM, respectively).
References: Nat Chem Biol. 2017 Nov; 13(11):1164-1171.
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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