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lixivaptan

lixivaptan

Item no.	V4748-500mg
Manufacturer	InvivoChem LLC
CASRN	168079-32-1
Amount	500mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4748CAS #:168079-32-1Purity >=98% Description: Lixivaptan (formerly known as VPA-985, WAY-VPA 985) is a novel, potent, selective and orally bioactive non-peptide antagonist of vasopressin receptor V2 with IC50 values of 1.2 and 2.3 nM for human and rat V2, respectively. Lixivaptan works by reducing the action of the hormone vasopressin that blocks fluid excretion. Lixivaptan acts by blocking vasopressin, an anti-diuretic hormone that causes the kidneys to retain water. When the body needs to remain hydrated under certain conditions, vasopressin can have protective effects. References: J Med Chem. 1998 Jul 2; 41(14):2442-4.; IDrugs. 2010 Nov; 13(11):782-92.
	Name: Lixivaptan CAS#: 168079-32-1 Chemical Formula: C27H21ClFN3O2 Exact Mass: 473.1306 Molecular Weight: 473.93 Elemental Analysis: C, 68.43; H, 4.47; Cl, 7.48; F, 4.01; N, 8.87; O, 6.75
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: VPA-985; VPA985; VPA 985; WAY-VPA-985; WAY VPA-985; WAY-VPA 985; WAY VPA 985; CRTX-080; CRTX080; CRTX 080; Lixivaptan IUPAC/Chemical Name: N-(3-chloro-4-(10, 11-dihydro-6H-benzo[e]pyrrolo[1, 2-a][1, 4]diazepine-5-carbonyl)phenyl)-5-fluoro-2-methylbenzamide InChi Key: UQSWTTDKNJDIRW-UHFFFAOYSA-N InChi Code: InChI=1S/C27H21ClFN3O2/c1-16-8-9-17(29)13-22(16)27(34)31-18-10-11-20(23(28)14-18)26(33)25-21-6-2-3-7-24(21)30-15-19-5-4-12-32(19)25/h2-5, 7-14, 30H, 6, 15H2, 1H3, (H, 31, 34) SMILES Code: O=C(NC1=CC=C(C(C2=C3C(NCC4=CC=CN42)=CC=CC3)=O)C(Cl)=C1)C5=CC(F)=CC=C5C

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Amount: 500mg

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