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bi-d-1416258-16-6

bi-d-1416258-16-6

Item no.	V4720-25mg
Manufacturer	InvivoChem LLC
CASRN	1416258-16-6
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4720CAS #:1416258-16-6Purity >=98% Description: (+/-)-BI-D is a novel and potent allosteric/noncatalytic site integrase inhibitor that binds integrase at the LEDGF/p75 binding site. It binds with higher affinity to a tetrameric form compared to a dimeric form of integrase. The binding of integrase (IN) to lens epithelium-derived growth factor (LEDGF)/p75 in large part determines the efficiency and specificity of HIV-1 integration. However, a significant residual preference for integration into active genes persists in Psip1 (the gene that encodes for LEDGF/p75) knockout (KO) cells. References: Nucleic Acids Res. 2012 Dec; 40(22):11518-30; ACS Med Chem Lett. 2014 Apr 16; 5(6):711-6.
	Molecular Weight: 405.49 Formula: C??H??NO? CAS No.: 1416258-16-6 SMILES: OC(C(OC(C)(C)C)C1=C(C(C=CC=C2)=C2N=C1C)C3=CC(CCCO4)=C4C=C3)=O
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	(+/-)-BI-D; (+/-)-BI D

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 11/8/2024

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