bi8622

Item no.	V4711-25mg
Manufacturer	InvivoChem LLC
CASRN	1875036-74-0
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4711CAS #:1875036-74-0Purity >=98% Description: BI-8622 is a novel, potent and specific inhibitor of the ubiquitin ligase HUWE1 with an IC50 of 3.1 uM. Deregulated expression of MYC is a driver of colorectal carcinogenesis, necessitating novel strategies to inhibit MYC function. The ubiquitin ligase HUWE1 (HECTH9, ARF-BP1, MULE) associates with both MYC and the MYC-associated protein MIZ1. References: EMBO Mol Med. 2014 Dec; 6(12):1525-41.
	Name: BI-8622 CAS#: 1875036-74-0 Chemical Formula: C25H26N6O Exact Mass: 426.2168 Molecular Weight: 426.52 Elemental Analysis: C, 70.40; H, 6.14; N, 19.70; O, 3.75
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BI8622; BI 8622; BI-8622 IUPAC/Chemical Name: N-(4-(Aminomethyl)phenyl)-6-(4-cyano-4-phenylpiperidin-1-yl)-5-methylpyrimidine-4-carboxamide InChi Key: IJHAXMJRQQTBPL-UHFFFAOYSA-N InChi Code: InChI=1S/C25H26N6O/c1-18-22(24(32)30-21-9-7-19(15-26)8-10-21)28-17-29-23(18)31-13-11-25(16-27, 12-14-31)20-5-3-2-4-6-20/h2-10, 17H, 11-15, 26H2, 1H3, (H, 30, 32) SMILES Code: O=C(C1=NC=NC(N2CCC(C3=CC=CC=C3)(C#N)CC2)=C1C)NC4=CC=C(CN)C=C4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 25mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 9 days

Compare

Add to wishlist

Recommend by mail