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bi-671800

bi-671800

Item no.	V4708-25mg
Manufacturer	InvivoChem LLC
CASRN	1093108-50-9
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4708CAS #:1093108-50-9Purity >=98% Description: BI-671800 is a novel, potent and highly specific antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 can be potentially used for the treatment of poorly controlled asthma. Description: BI-671800 is a novel, potent and highly specific antagonist of chemoattractant receptor-homologous molecule on Th2 cells (DP2/CRTH2), with IC50 values of 4.5 nM and 3.7 nM for PGD2 binding to CRTH2 in hCRTH2 and mCRTH2 transfected cells, respectively. BI-671800 can be potentially used for the treatment of poorly controlled asthma. Description50 References: Am J Physiol Lung Cell Mol Physiol. 2008 Nov; 295(5):L767-79.; Allergy Asthma Proc. 2017 Mar 1; 38(2):157-164. References: Am J Physiol Lung Cell Mol Physiol. 2008 Nov; 295(5):L767-79.; Allergy Asthma Proc. 2017 Mar 1; 38(2):157-164.References: Am J Physiol Lung Cell Mol Physiol. 2008 Nov; 295(5):L767-79.; Allergy Asthma Proc. 2017 Mar 1; 38(2):157-164.References
	Name: BI-671800 CAS#: 1093108-50-9 Chemical Formula: C25H26F3N5O3 Exact Mass: 501.19877 Molecular Weight: 501.5 Elemental Analysis: C, 59.87; H, 5.23; F, 11.36; N, 13.96; O, 9.57
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BI-671800; BI 671800; BI671800. IUPAC/Chemical Name: 5-Pyrimidineacetic acid, 4, 6-bis(dimethylamino)-2-((4-((4-(trifluoromethyl)benzoyl)amino)phenyl)methyl)- InChi Key: XEOSTBFUCNZKGS-UHFFFAOYSA-N InChi Code: InChI=1S/C25H26F3N5O3/c1-32(2)22-19(14-21(34)35)23(33(3)4)31-20(30-22)13-15-5-11-18(12-6-15)29-24(36)16-7-9-17(10-8-16)25(26, 27)28/h5-12H, 13-14H2, 1-4H3, (H, 29, 36)(H, 34, 35) SMILES Code: CN(C)c1c(c(nc(n1)Cc2ccc(cc2)NC(=O)c3ccc(cc3)C(F)(F)F)N(C)C)CC(=O)O

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 9/6/2024

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