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bi-689648

bi-689648

Item no.	V4701-50mg
Manufacturer	InvivoChem LLC
CASRN	1633009-87-6
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4701CAS #:1633009-87-6Purity >=98% Description: BI 689648 is a novel, potent and highly selective aldosterone synthase (AS) inhibitor that can attenuate the production of aldosterone directly and has been proposed as an alternative to mineralocorticoid receptor antagonists for blocking the pathologic effects of excess aldosterone. It can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively. BI 689648 represents an important step forward toward developing ASIs with greater potential for clinical success in cardiometabolic diseases. References: J Pharmacol Exp Ther. 2016 Oct; 359(1):142-50.
	Name: BI-689648 CAS#: 1633009-87-6 Chemical Formula: C16H18N4O2 Exact Mass: 298.143 Molecular Weight: 298.346 Elemental Analysis: C, 64.41; H, 6.08; N, 18.78; O, 10.73
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BI 689648; BI-689648; BI689648. IUPAC/Chemical Name: 6-(5-(methoxymethyl)pyridin-3-yl)-3, 4-dihydro-1, 8-naphthyridine-1(2H)-carboxamide InChi Key: DJFDCVNQDFICKV-UHFFFAOYSA-N InChi Code: InChI=1S/C16H18N4O2/c1-22-10-11-5-13(8-18-7-11)14-6-12-3-2-4-20(16(17)21)15(12)19-9-14/h5-9H, 2-4, 10H2, 1H3, (H2, 17, 21) SMILES Code: O=C(N1CCCC2=CC(C3=CC(COC)=CN=C3)=CN=C12)N

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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