« Back
Home /
sch-1473759

sch-1473759

Item no.	V4666-50mg
Manufacturer	InvivoChem LLC
CASRN	1094069-99-4
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4666CAS #:1094069-99-4Purity >=98% Description: SCH-1473759 is a novel, potent and selective aurora inhibitor with IC50s of 4 and 13 nM for aurora A and B, respectively. SCH 1473759 was active against a large panel of tumor cell lines from different tissue origin and genetic backgrounds. SCH-1473759 demonstrated potent mechanism-based activity, and activity was shown to be enhanced in combination with taxanes and KSP inhibitors. This information may be useful for optimizing the clinical efficacy of Aurora inhibitors. References: ACS Med Chem Lett. 2010 Jun 7; 1(5):214-8.; Cancer Chemother Pharmacol. 2011 Oct; 68(4):923-33. Related CAS : 1094069-99-4 (free base); 1094067-13-6 (HCl salt)
	Name: SCH-1473759 CAS#: 1094069-99-4 Chemical Formula: C20H26N8OS Exact Mass: 426.19503 Molecular Weight: 426.53844 Elemental Analysis: C, 56.32; H, 6.14; N, 26.27; O, 3.75; S, 7.52
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: SCH1473759; SCH-1473759; SCH 1473759. IUPAC/Chemical Name: 2-(ethyl((5-((6-methyl-3-(1H-pyrazol-4-yl)imidazo[1, 2-a]pyrazin-8-yl)amino)isothiazol-3-yl)methyl)amino)-2-methylpropan-1-ol SMILES Code: CC(C)(N(CC)CC1=NSC(NC2=NC(C)=CN3C2=NC=C3C4=CNN=C4)=C1)CO

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 10 days

Compare

Add to wishlist

Recommend by mail