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sb-224289

sb-224289

Item no.	V4611-10mg
Manufacturer	InvivoChem LLC
CASRN	180083-23-2
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4611CAS #:180083-23-2 Purity >=98% Description: SB-224289 hydrochloride is a novel, potent and selective 5-HT1B receptor antagonist with anxiolytic effect with pKi of 8.2. SB 224289 displays > 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. SB 224289 is a centrally active following oral administration in vivo. References: PLoS One. 2016 May 16; 11(5):e0154932.
	Name: SB 224289 CAS#: 180083-23-2 Chemical Formula: C32H32N4O3 Exact Mass: 520.2474 Molecular Weight: 520.63 Elemental Analysis: C, 73.82; H, 6.20; N, 10.76; O, 9.22
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: SB 224289; SB224289; SB-224289. IUPAC/Chemical Name: (1'-Methyl-6, 7-dihydro-5H-spiro(furo(2, 3-f)indole-3, 4'-piperidin)-5-yl)(2'-methyl-4'-(5-methyl-1, 2, 4-oxadiazol-3-yl)biphenyl-4-yl)methanone InChi Key: ATQMRMGXINTJHV-UHFFFAOYSA-N InChi Code: InChI=1S/C32H32N4O3/c1-20-16-25(30-33-21(2)39-34-30)8-9-26(20)22-4-6-23(7-5-22)31(37)36-13-10-24-17-29-27(18-28(24)36)32(19-38-29)11-14-35(3)15-12-32/h4-9, 16-18H, 10-15, 19H2, 1-3H3 SMILES Code: O=C(N1CCC2=C1C=C3C(OCC34CCN(C)CC4)=C2)C5=CC=C(C6=CC=C(C7=NOC(C)=N7)C=C6C)C=C5

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Amount: 10mg

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Delivery expected until 10/4/2024

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