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vortioxetine-aa21004

vortioxetine-aa21004

Item no.	V4425-10mg
Manufacturer	InvivoChem LLC
CASRN	508233-74-7 (free base)
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	508233-74-7
Available
Description	InvivoChem Cat #:V4425CAS #:508233-74-7 (free base)Purity >=98% Description: Vortioxetine (formerly known as Lu AA21004) is a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. Vortioxetine is an atypical antidepressant whichwas approved in 2013 by the FDA for the treatment of major depressive disorder (MDD) in adults. Vortioxetine is a so-called 'serotonin modulator and stimulator'. References: J Med Chem. 2011 May 12; 54(9):3206-21; J Pharmacol Exp Ther. 2012 Mar; 340(3):666-75. Related CAS: 960203-27-4 (HBr); 1253056-29-9 (lactate)
Molecular Weight (MW)	298.45
Formula	C18H22N2S.HBr
CAS No.	960203-27-4 (HBr); 508233-74-7 (free base); 1253056-29-9 (lactate)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 50 mg/mL
	Water:< 1 mg/mL
	Ethanol: N/A
Solubility (In vivo)	15% Captisol, pH 9: 10 mg/mL
Synonyms	LuAA21004, Lu-AA21004, Lu AA21004, AA21004, AA21004; AA-21004; AA 21004; Vortioxetine, vortioxetine hydrobromide, Brintellix
SMILES Code	CC1=CC=C(SC2=CC=CC=C2N3CCNCC3)C(C)=C1

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Amount: 10mg

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Delivery expected until 9/6/2024

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