InvivoChem Cat #:V4425CAS #:508233-74-7 (free base)Purity >=98%Description: Vortioxetine (formerly known as Lu AA21004) is a multimodal serotonergic agent which inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. Vortioxetine is an atypical antidepressant whichwas approved in 2013 by the FDA for the treatment of major depressive disorder (MDD) in adults. Vortioxetine is a so-called 'serotonin modulator and stimulator'.
References: J Med Chem. 2011 May 12; 54(9):3206-21; J Pharmacol Exp Ther. 2012 Mar; 340(3):666-75.
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