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etoricoxib

etoricoxib

Item no.	V4391-50mg
Manufacturer	InvivoChem LLC
CASRN	202409-33-4
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4391CAS #:202409-33-4 Purity >=98% Description: Etoricoxib (also known as MK-0663) is a non-steroidal anti-inflammatory drgu (NSAID) which acts as a selective and orally bioactive COX-2 inhibitor, with IC50s of 1.1 uM and 116 uM for COX-2 and COX-1 in human whole blood. Etoricoxib is a synthetic NSAID with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib binds specifically to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis. References: Asian Pac J Cancer Prev. 2010; 11(5):1329-33. Related CAS#: 202409-40-3 (HCl salt); 1131345-14-6 (Etoricoxib D4)
	Name: Etoricoxib CAS#: 202409-33-4 (free base); Chemical Formula: C18H15ClN2O2S Exact Mass: 358.0543 Molecular Weight: 358.8419 Elemental Analysis: C, 60.25; H, 4.21; Cl, 9.88; N, 7.81; O, 8.92; S, 8.94
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: L-791456, L791456, L 791456, MK-0663, MK 0663, MK0663; Arcoxia IUPAC/Chemical Name: 5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2, 3'-bipyridine InChi Key: MNJVRJDLRVPLFE-UHFFFAOYSA-N InChi Code: InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2, 22)23/h3-11H, 1-2H3 SMILES Code: O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O

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Amount: 50mg

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Delivery expected until 9/6/2024

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