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rogaratinib

rogaratinib

Item no.	V4215-25mg
Manufacturer	InvivoChem LLC
CASRN	1443530-05-9
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4215CAS #:1443530-05-9Purity >=98% Description: Rogaratinib (formerly also known as BAY-1163877) is a novel, orally available, potent and selective inhibitor of aberrant fibroblast growth factor receptor (FGFR). Rogaratinib inhibits the activity of FGFR-1, -2 and -3 kinases which are a family of receptor tyrosine kinases, and are upregulated in various tumor cell types and may be involved in tumor cell differentiation and proliferation, tumor angiogenesis, and tumor cell survival. Description: References: Oncogenesis. 2016 Jul 18; 5(7):e241. References:
	Name: Rogaratinib CAS#: 1443530-05-9 Chemical Formula: C23H26N6O3S Exact Mass: 466.1787 Molecular Weight: 466.56 Elemental Analysis: C, 59.21; H, 5.62; N, 18.01; O, 10.29; S, 6.87
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: Rogaratinib; BAY-1163877: BAY1163877: BAY 1163877 IUPAC/Chemical Name: 4-((4-amino-5-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)-6-(methoxymethyl)pyrrolo[2, 1-f][1, 2, 4]triazin-7-yl)methyl)piperazin-2-one InChi Key: HNLRRJSKGXOYNO-UHFFFAOYSA-N InChi Code: InChI=1S/C23H26N6O3S/c1-13-6-14-8-18(33-22(14)17(7-13)32-3)20-15(11-31-2)16(9-28-5-4-25-19(30)10-28)29-21(20)23(24)26-12-27-29/h6-8, 12H, 4-5, 9-11H2, 1-3H3, (H, 25, 30)(H2, 24, 26, 27) SMILES Code: O=C1NCCN(CC2=C(COC)C(C3=CC4=CC(C)=CC(OC)=C4S3)=C5C(N)=NC=NN52)C1

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Amount: 25mg

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Delivery expected until 9/6/2024

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