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Description: Bifonazole is a novel and potent imidazole antifungal drug. Bifonazole has dual mode of action by blocking the transformation of 24-methylendihydrolanosterol to desmethylsterol in fungi together with inhibition of HMG-CoA. This enables fungicidal properties against dermatophytes and distinguishes bifonazole from other antifungal drugs. Bifonazole is a marketed drug developed by Bayer under the trade name of Canespor in ointment form.
References: Dermatologica, 1984. 169 Suppl 1: p. 3-9.
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