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Description: Dasatinib metabolite M6 (also called Dasatinib carboxylic acid) is metabolite of Dasatinib generated by an oxidative metabolic reaction. Dasatinib is a potent and orally bioactive dual Bcr-Abl and Src family tyrosine kinase inhibitor.Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.
References: Biotransformation of 14Cdasatinib: in vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys. Drug Metab Dispos. 2008 Jul; 36(7):1341-56.
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