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firocoxib

firocoxib

Item no.	V4024-25mg
Manufacturer	InvivoChem LLC
CASRN	189954-96-9
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4024CAS #:189954-96-9Purity >=98% Description: Firocoxib (formerly known as ML 1785713) is a novel potent and selective cyclooxygenase (COX)-2 inhibitor with IC50 of 0.13 uM, with 58 fold sensitivity for COX2 Versus COX1. It is a non-steroidal anti-inflammatory drugs (NSAIDs) of the COX-2 inhibitor class, the conversion of arachidonic acid into prostaglandin is catalysed by the cyclo-oxygenases (COX-1/COX-2). Several studies indicate that COX-2 is overexpressed in actinic keratosis in humans and dogs. Firocoxib is a COX-2-selective inhibitor that blocks the biochemical activity of COX-2. Description: References: Vet Dermatol. 2013 Dec; 24(6):606-12, e147. References:
Molecular Weight (MW)	336.4
Formula	C17H20O5S
CAS No.	189954-96-9
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: >= 50 mg/mL
	Water: N/A
	Ethanol: N/A
Chemical Name	3-(Cyclopropylmethoxy)-4-(4-methylsulfonylphenyl)-5, 5-dimethylfuranone
Synonyms	ML 1, 785, 713; ML 1785713; Firocoxib; Equioxx; Previcox; ML-1, 785, 713; ML-1785713; ML1, 785, 713; ML1785713.
SMILES Code	CC1(C(=C(C(=O)O1)OCC2CC2)c3ccc(cc3)S(=O)(=O)C)C

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Amount: 25mg

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Delivery expected until 9/6/2024

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