ml-290

Item no.	V4015-100mg
Manufacturer	InvivoChem LLC
CASRN	1482500-76-4
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4015CAS #:1482500-76-4 Purity >=98% Description: ML-290, a 2-acetamido-N-phenylbenzamide analog, is a novel potent, selective and orally bioactive agonist of the relaxin/insulin-like family peptide receptor (RXFP1) and an activator of anti-fibrotic genes with an EC50 of 94 nM. It was identified from a dose responsive quantitative high throughput screen (qHTS) of > 350, 000 compounds against a human relaxin/insulin-like family peptide receptor (RXFP1) transfected HEK293?cell line. ML-290 has excellent in vivo PK properties with high levels of systemic exposure. ML-290 represents the first-in-class small-molecule agonists of RXFP1 and is a potent activator of anti-fibrotic genes. Description: References: Eur J Med Chem. 2018 Aug 5; 156:79-92. References:
Molecular Weight (MW)	506.5
Formula	C24H21F3N2O5S
CAS No.	1482500-76-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10mM
	Water: N/A
	Ethanol: N/A
Chemical Name	2-[(2-propan-2-yloxybenzoyl)amino]-N-[3-(trifluoromethylsulfonyl)phenyl]benzamide
Synonyms	ML290; ML 290; ML-290
SMILES Code	O=C(NC1=CC=CC(S(=O)(C(F)(F)F)=O)=C1)C2=CC=CC=C2NC(C3=CC=CC=C3OC(C)C)=O

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100mg

available

Delivery expected until 9/6/2024