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cp376395

cp376395

Item no.	V3997-250mg
Manufacturer	InvivoChem LLC
CASRN	175140-00-8
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3997CAS #:175140-00-8 Purity >=98% Description: CP 376395 is a novel potent, selective and orally bioactive antagonist of Corticotropin releasing factor 1 (CRF1) receptor. It is a clinical candidate that showed a significant positive food effect in dog and human after oral administration. Efforts to address the food effect issue led to the discovery of this orally active CRF 1 receptor antagonists CP 376395 which showed improved physicochemical properties while retaining desired pharmacological properties. CP 376395 was advanced to the clinic stage. References: J Med Chem. 2008 Mar 13; 51(5):1385-92. Related CAS#:1013933-37-3 (HCl); 175139-41-0 (CP-316311); 69938-75-6 (CP-28888)
Molecular Weight (MW)	312.46
Formula	C20H28N2O
CAS No.	175140-00-8 (free base)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: >= mg/mL
	Water: N/A
	Ethanol: N/A
Chemical Name	N, N-diethyl-2-(mesityloxy)-3, 6-dimethylpyridin-4-amine
Synonyms	CP-376395; CP 376395; CP376395; CP-376, 395; CP 376, 395; CP376, 395
SMILES Code	CCN(CC)C1=C(C)C(OC2=C(C)C=C(C)C=C2C)=NC(C)=C1

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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