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gne-1858

gne-1858

Item no.	V39652-5mg
Manufacturer	InvivoChem LLC
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V39652CAS #:Purity >=98% GNE-1858 is a novel, highly potent and ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor, with IC50s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA, respectively. References: Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer. Structure. 2019 Jan 2; 27(1):125-133.e4.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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