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lofexidine

lofexidine

Item no.	V3894-50mg
Manufacturer	InvivoChem LLC
CASRN	31036-80-3
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3894CAS #:31036-80-3Purity >=98% Description: Lofexidine (brand name Lucemyra among others), an analog of Clonidine, is a medication historically used to treat high blood pressure, but more commonly used to help with the physical symptoms of opioid withdrawal. It is an alpha2A adrenergic receptor agonist that has been approved for use by the Food and Drug Administration in the United States in 2018. The possibility of using lofexidine to treat alcohol withdrawal symptoms has been investigated, and has not yet been shown to be an effective treatment.5 It is also used in treatment of cases suffering from postmenopausal hot flashes. References: J Addict Med. 2018 Nov 29. doi: 10.1097/ADM.0000000000000473; J Subst Abuse Treat. 2018 Aug; 91:1-11. Related CAS#:21498-08-8 (HCl)
Molecular Weight (MW)	259.13
Formula	C11H12Cl2N2O
CAS No.	31036-80-3 (free)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: N/A
	Ethanol: N/A
Chemical Name	2-[1-(2, 6-dichlorophenoxy)ethyl]-4, 5-dihydro-1H-imidazole
Synonyms	Brand name Lucemyra; Lofexidine HCl; Lofexidine Hydrochloride; Lofetensin; Loxacor; Lofexidine mono-hydrochloride; lofexidine (+-)-isomer
SMILES Code	CC(C1=NCCN1)OC2=C(Cl)C=CC=C2Cl

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