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haemanthamine

haemanthamine

Item no.	V38789-1g
Manufacturer	InvivoChem LLC
CASRN	466-75-1
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V38789CAS #:466-75-1Purity >=98% Description: Haemanthamine is a naturally occuring crinine-type alkaloid extracted from the Amaryllidaceae plants with highly potent anticancer activity. Haemanthamine HCl targets ribosomal that inhibits protein biosynthesis during the elongation stage of translation. Haemanthamine HCl has pro-apoptotic, antioxidant, antiviral, antimalarial and anticonvulsant activities. References: 1. Pellegrino S, et al. The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth. Structure. 2018 Mar 6; 26(3):416-425.e4. 2. Seifrtova M, et al. Haemanthamine alters sodium butyrate-induced histone acetylation, p21WAF1/Cip1 expression, Chk1 and Chk2 activation and leads to increased growth inhibition and death in A2780 ovarian cancer cells. Phytomedicine. 2017 Nov 15; 35:1-10.

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