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epetraborole-r-mandelate

epetraborole-r-mandelate

Item no.	V3638-10mg
Manufacturer	InvivoChem LLC
CASRN	1234563-15-5
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3638CAS #:1234563-15-5 Purity >=98% Description: Epetraborole R-Mandelate (also known as GSK2251052 and AN3365) is a novel, potent and selective leucyl-tRNA synthetase (LeuRS) inhibitor, which inhibits protein synthesis by binding to the terminal adenosine ribose (A76) of leucyl-tRNA synthetase. Epetraborole was under investigation for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. GSK2251052 is a novel boron-containing antibiotic that inhibits bacterial leucyl tRNA synthetase. All Clostridium perfringens strains had GSK2251052 MICs of > 32 ug/ml. References: Antimicrob Agents Chemother. 2013 May; 57(5):2401-4.; Antimicrob Agents Chemother. 2015 Jan; 59(1):289-98. Related CAS#:1234563-16-6 (HCl); 1093643-37-8 (free base)
	Name: Epetraborole R-Mandelate CAS#: 1234563-15-5 Chemical Formula: C19H24BNO7 Exact Mass: Molecular Weight: 389.21 Elemental Analysis: C, 58.63; H, 6.22; B, 2.78; N, 3.60; O, 28.77
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: Epetraborole R-Mandelate; Epetraborole R Mandelate Chemical Name: 3-[[(3S)-3-(Aminomethyl)-1-hydroxy-3H-2, 1-benzoxaborol-7-yl]oxy]propan-1-ol (R)-mandelate InChi Key: GKQOYBLEEYTDIB-DEZAYANASA-N InChi Code: InChI=1S/C11H16BNO4.C8H8O3/c13-7-10-8-3-1-4-9(16-6-2-5-14)11(8)12(15)17-10; 9-7(8(10)11)6-4-2-1-3-5-6/h1, 3-4, 10, 14-15H, 2, 5-7, 13H2; 1-5, 7, 9H, (H, 10, 11)/t10-; 7-/m11/s1 SMILES Code: OB1O[CH](CN)C2=CC=CC(OCCCO)=C21.O[CH](C3=CC=CC=C3)C(O)=O

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Amount: 10mg

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Delivery expected until 9/6/2024

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