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Description: Warangalone is an isoflavonoid anti-malarial compound isolated from the insecticidal plant Derris scandens that acts as a powerful inhibitor of protein kinase A. It can inhibit the growth of both strains of parasite 3D7 (chloroquine sensitive) and K1 (chloroquine resistant) with IC50s of 4.8 ug/mL and 3.7 ug/mL, respectively. Warangalone can also inhibit cyclic AMP-dependent protein kinase catalytic subunit (cAK) with an IC50 of 3.5 uM.
References: Indo. J. Chem., 2009, 9 (2), 308-311.; Phytochemistry. 1997 Mar; 44(5):787-96.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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