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bms-066

bms-066

Item no.	V3471-100mg
Manufacturer	InvivoChem LLC
CASRN	914946-88-6
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3471CAS #:914946-88-6 Purity >=98% Description: BMS-066 is a novel and potent tricyclic pseudokinase inhibitors of IKKbeta/Tyk2 with IC50s of 9 nM and 72 nM, respectively. It demonstrates potent in vitro potency, acceptable pharmacokinetic and physicochemical properties, and efficacy when dosed orally in a mouse model of inflammatory bowel disease. References: J Biol Chem. 2015 Apr 24; 290(17):11061-74.
	Name: BMS-066 CAS#: 914946-88-6 Chemical Formula: C19H21N7O2 Exact Mass: 379.17567 Molecular Weight: 379.42 Elemental Analysis: C, 60.15; H, 5.58; N, 25.84; O, 8.43
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BMS-066; BMS 066; BMS066 Chemical Name: 2-methoxy-N-((6-(1-methyl-4-(methylamino)-1, 5-dihydroimidazo[4, 5-d]pyrrolo[2, 3-b]pyridin-7-yl)pyridin-2-yl)methyl)acetamide InChi Key: ULTCRVJUAZCGPP-UHFFFAOYSA-N InChi Code: InChI=1S/C19H21N7O2/c1-20-19-16-17(26(2)10-22-16)12-7-14(24-18(12)25-19)13-6-4-5-11(23-13)8-21-15(27)9-28-3/h4-7, 10H, 8-9H2, 1-3H3, (H, 21, 27)(H2, 20, 24, 25) SMILES Code: O=C(NCC1=NC(C2=CC3=C(N(C)C=N4)C4=C(NC)NC3=N2)=CC=C1)COC

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Amount: 100mg

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