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bms-986020

bms-986020

Item no.	V3470-250mg
Manufacturer	InvivoChem LLC
CASRN	1257213-50-5
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3470CAS #:1257213-50-5Purity >=98% Description: BMS-986020 (also known as AM152 and AP-3152 free acid) is a novel, potent and selective LPA1 (lysophosphatidic acid) antagonist. Currently BMS-986020 is in Phase 2 clinical trial for the treatment of idiopathic pulmonary fibrosis. BMS-986020 selectively inhibits the LPA receptor, which is involved in binding of the signaling molecule lysophosphatidic acid, which in turn is involved in a host of diverse biological functions like cell proliferation, platelet aggregation, smooth muscle contraction, chemotaxis, and tumor cell invasion, among others. References: Exp Cell Res. 2015 May 1; 333(2):171-7.
	Name: BMS-986020 CAS#: 1257213-50-5 Chemical Formula: C29H26N2O5 Exact Mass: 482.1842 Molecular Weight: 482.536 Elemental Analysis: C, 72.19; H, 5.43; N, 5.81; O, 16.58
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: AM152; AM 152; AM-152; BMS-986020; BMS986020; BMS 986020; AP-3152 free acid Chemical Name: (R)-1-(4'-(3-methyl-4-(((1-phenylethoxy)carbonyl)amino)isoxazol-5-yl)-[1, 1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid InChi Key: GQBRZBHEPUQRPL-LJQANCHMSA-N InChi Code: InChI=1S/C29H26N2O5/c1-18-25(30-28(34)35-19(2)20-6-4-3-5-7-20)26(36-31-18)23-10-8-21(9-11-23)22-12-14-24(15-13-22)29(16-17-29)27(32)33/h3-15, 19H, 16-17H2, 1-2H3, (H, 30, 34)(H, 32, 33)/t19-/m1/s1 SMILES Code: O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[CH](C)C5=CC=CC=C5)=O)C(C)=NO4)C=C3)C=C2)CC1)O

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Amount: 250mg

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Delivery expected until 9/6/2024

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