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ibiglustat

ibiglustat

Item no.	V3367-250mg
Manufacturer	InvivoChem LLC
CASRN	1401090-53-6
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3367CAS #:1401090-53-6Purity >=98% Description: Ibiglustat (formerly known as Venglustat; SAR402671; GZ402671; GZ-452; Genz-682452) is a novel, brain-penetrant, potent and selective allosteric Glucosylceramide synthase (GCS) inhibitor and ceramide glucosyltransferase inhibitor. It has the potential for treating PD Parkinson’s disease and SRT in Fabry’s and Gaucher’s. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthesis of GL-3. Ibiglustat is potentially useful for treating Fabry disease. Fabry disease is a rare lysosomal storage disorder, which results in abnormal tissue deposits of a particular fatty substance called globotriaosylceramide (GL-3 or Gb3) throughout the body. Description: References: J Inherit Metab Dis. 2014 Nov; 37(6):1013-22.; Future Med. Chem. (2017) 9(14), 1687–1700. References:
	Name: Ibiglustat CAS#: 1401090-53-6 Chemical Formula: C20H24FN3O2S Exact Mass: 389.1573 Molecular Weight: 389.49 Elemental Analysis: C, 61.68; H, 6.21; F, 4.88; N, 10.79; O, 8.22; S, 8.23
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: Venglustat; SAR402671; SAR-402671; SAR 402671; GZ-402671; GZ402671; GZ402671; Genz-682452-AA; Ibiglustat; GZ-452; Genz-682452 Chemical Name: (3S)-1-azabicyclo[2.2.2]octan-3-yl N-{2-[2-(4-fluorophenyl)- 1, 3-thiazol-4-yl]propan-2-yl}carbamate InChi Key: YFHRCLAKZBDRHN-MRXNPFEDSA-N InChi Code: InChI=1S/C20H24FN3O2S/c1-20(2, 17-12-27-18(22-17)14-3-5-15(21)6-4-14)23-19(25)26-16-11-24-9-7-13(16)8-10-24/h3-6, 12-13, 16H, 7-11H2, 1-2H3, (H, 23, 25)/t16-/m1/s1 SMILES Code: O=C(O[CH]1CN2CCC1CC2)NC(C)(C3=CSC(C4=CC=C(F)C=C4)=N3)C

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Amount: 250mg

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Delivery expected until 9/6/2024

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