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Description: ML-109 (CID-25246343) is a novel, potent and full thyroid stimulating hormone receptor (TSHR) agonist with an EC50 of 40 nM. It is the first selective and orally available small-molecule TSHR agonist, and the probe will be a useful pharmacological tool to study TSHRbiology in thyroidal and extrathyroidal tissues.
References: Neumann S, et al. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Proc Natl Acad Sci U S A. 2009 Jul 28; 106(30):12471-6.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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