« Back
Home /
rosuvastatin-d6-calcium

rosuvastatin-d6-calcium

Item no.	V3297-50mg
Manufacturer	InvivoChem LLC
CASRN	N/A (Rosuvastatin D6 Calcium); N/A ( Rosuvastatin D6 Sodium); 1279031-70-7 (Rosuvastatin D3 Sodium); 287714-41-4 (Rosuvastatin); 147098-20-2 (Rosuvastatin calcium)
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3297CAS #:N/A (Rosuvastatin D6 Calcium); N/A ( Rosuvastatin D6 Sodium); 1279031-70-7 (Rosuvastatin D3 Sodium); 287714-41-4 (Rosuvastatin); 147098-20-2 (Rosuvastatin calcium)Purity >=98% Description: Rosuvastatin D6 Calcium is deuterium labeled Rosuvastatin Calcium (also known as S-4522, Rosuvastatin hemicalcium; ZD 4522 Calcium and ZD 4522, trade name: Crestor) which is a member of the statin class of drugs and a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay. Rosuvastatin belongs to the statin class that is used for the treatment of high cholesterol and related conditions such as dyslipidemia, and to prevent cardiovascular disease. Its approximate elimination half life is 19 h and its time to peak plasma concentration is reached in 3–5 h following oral administration. In 2013 Crestor was the fourth-highest selling drug in the United States, accounting for approx. $5.2 billion in sales. Description: References: Clin Pharmacol Ther. 2004 May; 75(5):455-63; Bioorg Med Chem. 1997 Feb; 5(2):437-44. References:
Molecular Weight (MW)	506.61
Formula	C??H??D?FN?O?S . ?/? Ca
CAS No.	1279031-70-7 (Rosuvastatin D3 Sodium); 287714-41-4 (Rosuvastatin); 147098-20-2 (Rosuvastatin calcium)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10mM)
	Water:
	Ethanol:
Solubility (In vivo)	4% DMSO+30% PEG 300+dd H2O: 10 mg/mL
Synonyms	Rosuvastatin calcium (ZD 4522; ZD-4522; ZD4522; S-4522; S 4522; S4522; ZD 4522 calcium salt; Rosuvastatin calcium; Brand name: Crestor.)
Chemical Name	Rosuvastatin calcium: calcium (3R, 5S, E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3, 5-dihydroxyhept-6-enoate
SMILES Code	O=C([O-])C[CH](O)C[CH](O)/C=C/C1=C(C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50mg

available

Delivery expected until 9/6/2024

Express Delivery: Save 14 days

Compare

Add to wishlist

Recommend by mail