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zk824859

zk824859

Item no.	V31391-50mg
Manufacturer	InvivoChem LLC
CASRN	2271122-53-1
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V31391CAS #:2271122-53-1Purity >=98% Description: ZK824859 is a novel, potent, orally bioavailable, and selective urokinase plasminogen activator (uPA) inhibitor with IC50s of 79?nM, 1580?nM and 1330?nM for human uPA, tPA, and plasmin, respectively. ZK824859 showed activity to lower clinical scores when dosed in either acute or chronic mouse EAE mode. ZK824859 showed activity to lower clinical scores when dosed in either acute or chronic mouse EAE mode. References: Islam I, et al. Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis. Bioorg Med Chem Lett. 2018 Nov 1; 28(20):3372-3375. Related CAS #: 2254001-81-3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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