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a-192621

a-192621

Item no.	V3066-10mg
Manufacturer	InvivoChem LLC
CASRN	195529-54-5
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3066CAS #:195529-54-5Purity >=98% Description: A-192621 is an antagonist of endothelin-B. Endothelins (ETs), 21-amino-acid peptides involved in the pathogenesis of various diseases, bind to ET(A) and ET(B) receptors to initiate their effects. A-192621 can markedly enhance MAP, TPR, and mesenteric, and the renal constrictor effects of ET-1. A-192621 was more effective than IRL-2500 in blocking IRL-1620-induced vasoconstriction, but both augmented constrictor responses to ET-1. Description: References: Clin Sci (Lond). 2002 Aug; 103 Suppl 48:112S-117S. References:
Molecular Weight (MW)	558.67
Formula	C33H38N2O6
CAS No.	195529-54-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: N/A
	Ethanol: N/A
SMILES	O=C([CH]1[CH](C2=CC=C(OCCC)C=C2)N(CC(NC3=C(CC)C=CC=C3CC)=O)C[CH]1C4 =CC=C(OCO5)C5=C4)O
Synonyms	A-192621; A 192621; A192621; A-192621-1

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Amount: 10mg

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Delivery expected until 9/6/2024