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Description: Ketoisovaleric acid (3-Methyl-2-oxobutanoic acid) is a precursor for the biosynthesis of pantothenic acid in Escherichia coli.
References: MAAS WK, et al. alpha-Ketoisovaleric acid, a precursor of pantothenic acid in Escherichia coli. J Bacteriol. 1953 Apr; 65(4):388-93.2. Schauder P, et al. Oral administration of alpha-ketoisovaleric acid or valine in humans: blood kinetics and biochemical effects. J Lab Clin Med. 1984 Apr; 103(4):597-605.3. Coitinho AS, et al. Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain Res. 2001 Mar 9; 894(1):68-73.
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