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synta66

synta66

Item no.	V29155-50mg
Manufacturer	InvivoChem LLC
CASRN	835904-51-3
Amount	50mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V29155CAS #:835904-51-3Purity >=98% Description: Synta66 is a novel and potent inhibitor/blocker of Ca2+ entry via store-operated Ca2+ release-activated Ca2+ (CRAC) channels. As an inhibitor of store-operated calcium entry channel Orai, it forms the pore of the CRAC channel, and is used for the research of neurological disease. References: 1. MolnarT, et al. Store-Operated Calcium Entry in Müller Glia Is Controlled bySynergistic Activation of TRPC and Orai Channels. J Neurosci. 2016 Mar16; 36(11):3184-98. 2. vanKruchten R, et al. Antithrombotic potential of blockers ofstore-operated calcium channels in platelets. Arterioscler Thromb VascBiol. 2012 Jul; 32(7):1717-23. 3. WajdnerHE, et al. Orai and TRPC channel characterization in FcepsilonRI-mediatedcalcium signaling and mediator secretion in human mast cells. PhysiolRep. 2017 Mar; 5(5).

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50mg

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