ac710

Item no.	V2880-25mg
Manufacturer	InvivoChem LLC
CASRN	1351522-04-7
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2880CAS #:1351522-04-7 Purity >=98% Description: AC710 is a potent, orally bioactive, and selective inhibitor of PDGFR (platelet-derived growth factor receptor) family kinase with Kd values of 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRalpha and PDGFRbeta, respectively. As a PDGFR inhibitor, AC710 has potential anticancer activity. Results from a mouse tumor xenograft, a collagen-induced arthritis model, and a 7 day rat in vivo tolerability study culminated in the selection of AC710 as a preclinical development candidate. References: ACS Med Chem Lett. 2012 Sep 24; 3(12):997-1002 Related CAS#: 1351522-04-7 (free base); 1351522-05-8 (mesylate)
Molecular Weight (MW)	562.7
Formula	C31H42N6O4
CAS No.	1351522-04-7 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 14 mg/mL
	Water: < 1 mg/mL
	Ethanol: N/A
Solubility (In vivo)	O=C(NC1=CC=C(NC(NC2=NOC(C(C)(C)C)=C2)=O)C=C1)C3=NC=C(OC4CC(C)(C)N(CC)C(C)(C)C4)C=C3
Synonyms	AC 710; AC710; AC-710.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 25mg

available

Delivery expected until 10/4/2024

Express Delivery: Save 8 days

Compare

Add to wishlist

Recommend by mail