Comparison

guadecitabine-sodium

Item no. V28733-10mg
Manufacturer InvivoChem LLC
CASRN 929904-85-8
Amount 10mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V28733CAS #:929904-85-8Purity >=98%

Description: Guadecitabine sodium (SGI-110 sodium; S-110 sodium), a dinucleotide consisting of 5-Aza-CdR followed by a deoxyguanosine, is a novel and potent DNA methyltransferases (DNMT) inhibitor with the potential to be used for treating acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS).

References:

1. Yoo CB, et al. Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides. Cancer Res. 2007 Jul 1; 67(13):6400-8.

2. ChuangJC, et al. S-110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, isan effective DNA methylation inhibitor in vivo and can reduce tumorgrowth. Mol Cancer Ther. 2010 May; 9(5):1443-50.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10mg
Available: In stock
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