Comparison

ulixertinib-hcl

Item no. V27837-5mg
Manufacturer InvivoChem LLC
CASRN 1956366-10-1
Amount 5mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 1956366-10-1
Available
Description
InvivoChem Cat #:V27837CAS #:1956366-10-1Purity >=98%

Description: Ulixertinib (formerly also known as BVD-523 and VRT752271) is a novel, potent, orally bioactive, highly selective, ATP-competitive and reversible ERK1/ERK2 inhibitor with IC50 of< 0.3 nM for ERK2. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways.

References: J Med Chem. 2015 Jun 11; 58(11):4790-801.

Related CAS #: 1956366-10-1 (HCl) 869886-67-9 (free base) 1975172-95-2 (HCl hydrate)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5mg
Available: In stock
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