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atipamezole-hcl

atipamezole-hcl

Item no.	V2589-100mg
Manufacturer	InvivoChem LLC
CASRN	104075-48-1
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2589CAS #:104075-48-1Purity >=98% Description: Atipamezole (Antisedan, MPV-1248) is a synthetic alpha2 adrenergic receptor antagonist with a Ki of 1.6 nM. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride was a potent inhibitor of aldosterone release (range 10-1000 nM). In receptor binding studies ( 3H-clonidine and 3H-prazosin displacement) an alpha 2/alpha 1 selectivity ratio of 8526 was obtained for atipamezole, while idazoxan and yohimbine showed ratios of 27 and 40, respectively. References: J Neural Transm Park Dis Dement Sect. 1992; 4(2):99-106; Eur J Pharmacol. 1992 Nov 24; 224(1):27-38. Related CAS: 104054-27-5 (free); 104075-48-1 (HCl)
Molecular Weight (MW)	248.75
Formula	C14H16N2.HCl
CAS No.	104075-48-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 12 mg/mL (48.24mM)
	Water: 21 mg/mL (84.4 mM)
	Ethanol: 49 mg/mL (197 mM)
Other info	Chemical Name: 4-(2-ethyl-2, 3-dihydro-1H-inden-2-yl)-1H-imidazole hydrochloride InChi Key: PCCVCJAQMHDWJY-UHFFFAOYSA-N InChi Code: InChI=1S/C14H16N2.ClH/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14; /h3-6, 9-10H, 2, 7-8H2, 1H3, (H, 15, 16); 1H SMILES Code: CCC1(C2=CNC=N2)CC3=C(C=CC=C3)C1.[H]Cl
Synonyms	Antisedan, MPV-1248 hydrochloride, MPV1248 hydrochloride, MPV 1248 hydrochloride

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Amount: 100mg

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