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Description: Ulipristal acetate (also known as CDB-2914) is a potent and selective SPRM (selective progesterone receptor modulator) for emergency contraception after an unprotected intercourse or contraceptive failure. Ulipristal acetate has partial agonistic as well as antagonistic effects on the progesterone receptor. It also binds to the glucocorticoid receptor, but has no relevant affinity to the estrogen, androgen and mineralocorticoid receptors. Ulipristal acetate dose dependently suppressed progesterone-induced acrosome reaction and hyperactivation in human spermatozoa.
References: J Steroid Biochem Mol Biol. 2004 Mar; 88(3):277-88; Clin Ther. 2012 Jan; 34(1):24-36.
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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