InvivoChem Cat #:V23915CAS #:185197-70-0Purity >=98%Description: (R)-Lercanidipine is the R-enantiomer of Lercanidipine.Lercanidipine HCl (REC-15-237, Lercadip, Lerdip, Zanidip) is a 3rdgeneration and lipophilic CCB (calcium channel blocker) of thedihydropyridine class and amedication used to treat high blood pressure, with long lastingantihypertensive action and reno-protective effect. It works by relaxingand opening the blood vessels allowing the blood to circulate morefreely around the body. This lowers the blood pressure and allows theheart to work more efficiently.
References:
1. Barrios, V., et al., Lercanidipine is an effective and well toleratedantihypertensive drug regardless the cardiovascular risk profile: TheLAURA study. Int J Clin Pract, 2006. 60(11): p. 1364-70.
2. Burnier, M., M. Pruijm, and G. Wuerzner, Treatment of essential hypertensionwith calcium channel blockers: what is the place of lercanidipine?Expert Opin Drug Metab Toxicol, 2009. 5(8): p. 981-7.
3. GrassiG, et, al. Lercanidipine in the Management of Hypertension: An Update. JPharmacol Pharmacother. Oct-Dec 2017; 8(4):155-165.
4.Clinical efficacy of calcium channel blockers slow the third generationof lercanidipine in the treatment of patients with arterialhypertension and metabolic disorders (review). Georgian Med News. 2015Feb; (239):51-6. Review. Russian.
Related CAS: 187731-34-6 ((R)-Lercanidipine HCl); 132866-11-6 (Lercanidipine HCl) 100427-26-7 (Lercanidipine free base)
187731-34-6 ((R)-Lercanidipine HCl); 132866-11-6 (Lercanidipine HCl) 100427-26-7 (Lercanidipine free base) 100427-26-7 (Lercanidipine free base)