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Description: GC376 sodium is a potent inhibitor of 3C-like proteases (3CLpro) with IC50 values ranging from 0.49 to 4.35 uM. GC376 has the potential to be used in treating cats with certain presentations of FIP and is a promising targeted antiviral drug therapy.
References: 1.Kim Y, et al. Broad-spectrum antivirals against 3C or 3C-like proteasesof picornaviruses, noroviruses, and coronaviruses. J Virol. 2012Nov; 86(21):11754-62.; 2.Pedersen NC, et al. Efficacy of a 3C-like protease inhibitor intreating various forms of acquired feline infectious peritonitis. JFeline Med Surg. 2018 Apr; 20(4):378-392.
Related CAS #: 1416992-39-6 (sodium salt); 1417031-79-8 (free acid)
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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