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cefditoren-pivoxil

cefditoren-pivoxil

Item no.	V2080-250mg
Manufacturer	InvivoChem LLC
CASRN	117467-28-4
Amount	250mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2080CAS #:117467-28-4 Purity >=98% Description: Cefditoren Pivoxil (also named ME-1207) is a broad-spectrum and 3rd-generation antibiotic against Gram-negative and Gram-positive bacteria. Cefditoren has MIC50/MIC90 results for Moraxella catarrhalis and Haemophilus influenzae of 0.12/0.5 and < or = 0.008/0.015 mg/mL, respectively. Cefditoren (MIC(90), 0.5 mg/mL) is 4- to 128-fold more active than comparison beta-lactams against the pneumoococci and was the most potent beta-lactam (including penicillin) versus beta-haemolytic streptococci. Cefditoren (MIC(90) in mg/mL/% susceptible) activity against all tested H. influenzae (0.03/100) and M. catarrhalis (0.06-0.5/100) is comparable to Cefixime and significantly greater than cefaclor. References: Diagn Microbiol Infect Dis. 1998 Aug; 31(4):573-8; Diagn Microbiol Infect Dis. 2000 Jun; 37(2):99-105; Drugs Exp Clin Res. 1994; 20(4):127-47. Related CAS #: 104146-53-4 (sodium); 104145-95-1 (free); 117467-28-4 (pivoxil); 442852-27-9 (tosylate); 442852-31-5 (oxalate); 442852-33-7 (sulfate); 1448435-17-3 (HCl); 442852-29-1 (mesylate)
Molecular Weight (MW)	620.72
Formula	C25H28N6O7S3
CAS No.	117467-28-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 100 mg/mL (161.1 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Other info	Chemical Name: (pivaloyloxy)methyl (6R, 7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((Z)-2-(4-methylthiazol-5-yl)vinyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate InChi Key: AFZFFLVORLEPPO-UVYJNCLZSA-N InChi Code: InChI=1S/C25H28N6O7S3/c1-12-15(41-10-27-12)7-6-13-8-39-21-17(29-19(32)16(30-36-5)14-9-40-24(26)28-14)20(33)31(21)18(13)22(34)37-11-38-23(35)25(2, 3)4/h6-7, 9-10, 17, 21H, 8, 11H2, 1-5H3, (H2, 26, 28)(H, 29, 32)/b7-6-, 30-16-/t17-, 21-/m1/s1 SMILES Code: CC1=C(SC=N1)/C=C\C2=C(N3[CH]([CH](C3=O)NC(=O)/C(=N\OC)/C4=CSC(=N4)N)SC2)C(=O)OCOC(=O)C(C)(C)C
Synonyms	ME-1207; ME 1207; ME1207; CDTR-PI; Spectracef; Meiact.

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Amount: 250mg

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