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eltanexor

eltanexor

Item no.	V20471-10mg
Manufacturer	InvivoChem LLC
CASRN	1642300-52-4
Amount	10mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V20471CAS #:1642300-52-4Purity >=98% Description: Eltanexor (is discontinued) formerly known as KPT-8602, is a second-generation exportin-1 inhibitor. KPT-8602 displays potent activity against acute lymphoblastic leukemia. KPT-8602 is well tolerated and highly active against AML blasts and leukemia-initiating cells. Eltanexor shows improved efficacy and in vivo tolerability in hematological malignancies. Reference: Vercruysse T, De Bie J, Neggers J, Jacquemyn M, Vanstreels E, Schmid-Burgk JL, Hornung V, Baloglu E, Landesman Y, Senapedis W, Shacham S, Dagklis A, Cools J, Daelemans D. The second-generation exportin-1 inhibitor KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia. Clin Cancer Res. 2016 Oct 25. pii: clincanres.1580.2016. Epub ahead of print PubMed PMID: 27780859.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10mg

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