InvivoChem Cat #:V20351CAS #:143-67-9Purity >=98%Description: Vinblastine sulfate (also known as NSC49842; Vincaleukoblastine), a natural alkaloid extracted from the plant Vinca rosea Linn, is an approvedanticancer drug and a potent mitotic inhibitor that inhibitsmicrotubule formation and suppresses nAChR activity with IC50 of 8.9 uMin a cell-free assay, it is used to treat certain kinds of cancer.Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumorcells in the M phase of the cell cycle.
References: Proc Soc Exp Biol Med. 1993 Jul; 203(3):372-6; Oncogene. 2003 Sep 25; 22(41):6458-61.
Related CAS #:143-67-9 (sulfate) 865-21-4 (free)
Description: Vinblastine sulfate (also known as NSC49842; Vincaleukoblastine), a natural alkaloid extracted from the plant Vinca rosea Linn, is an approvedanticancer drug and a potent mitotic inhibitor that inhibitsmicrotubule formation and suppresses nAChR activity with IC50 of 8.9 uMin a cell-free assay, it is used to treat certain kinds of cancer.Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumorcells in the M phase of the cell cycle.
References: Proc Soc Exp Biol Med. 1993 Jul; 203(3):372-6; Oncogene. 2003 Sep 25; 22(41):6458-61.
Related CAS #:143-67-9 (sulfate) 865-21-4 (free)