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Description: D-Lin-MC3-DMA is a potent and ionizable / cationic lipid that has been usef for lipid nanoparticles (LNPs) to deliver the siRNA. D-Lin-MC3-DMA is useful for design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. LNP systems containing D-Lin-MC3-DMA can be highly effective, non-toxic pDNA delivery systems for gene expression both in vitro and in vivo.
References: Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine. 2017 May; 13(4):1377-1387.; Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles. Proc Natl Acad Sci U S A. 2018 Apr 10; 115(15):E3351-E3360. doi: 10.1073/pnas.1720542115. Epub 2018 Mar 27.
Related CAS #: 1224606-06-7; 1258299-72-7 (deleted)
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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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