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nicaraven

nicaraven

Item no.	V1964-1g
Manufacturer	InvivoChem LLC
CASRN	79455-30-4
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1964CAS #:79455-30-4 Purity >=98% Description: Nicaraven is a hydroxyl radical scavenger with antivasospastic and neuroprotective effects. Nicaraven causes a dose-dependent, slight inhibition of poly (ADP-ribose) synthetase activation, possibly due to a direct inhibitory effect on the catalytic activity of poly (ADP-ribose) synthetase in RAW murine macrophages stimulated with peroxynitrite. Nicaraven partially protects against the peroxynitrite-induced suppression of mitochondrial respiration in RAW macrophages and causes a slight, dose-dependent inhibition of nitrite production in RAW macrophages stimulated with bacterial lipopolysaccharide. References: Shock. 2000 Feb; 13(2):126-34; Surgery. 2000 Jun; 127(6):661-9.
Molecular Weight (MW)	284.31
Formula	C15H16N4O2
CAS No.	79455-30-4
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 57 mg/mL (200.5 mM)
	Water: 57 mg/mL (200.5 mM)
	Ethanol: 57 mg/mL (200.5 mM)
Other info	Chemical Name: N, N'-(propane-1, 2-diyl)dinicotinamide InChi Key: KTXBOOWDLPUROC-UHFFFAOYSA-N InChi Code: InChI=1S/C15H16N4O2/c1-11(19-15(21)13-5-3-7-17-10-13)8-18-14(20)12-4-2-6-16-9-12/h2-7, 9-11H, 8H2, 1H3, (H, 18, 20)(H, 19, 21) SMILES Code: CC(NC(C1=CC=CN=C1)=O)CNC(C2=CC=CN=C2)=O
Synonyms	N, N'-(propane-1, 2-diyl)dinicotinamide

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