Comparison

fph2-brd-9424

Item no. V1930-50mg
Manufacturer InvivoChem LLC
CASRN 957485-64-2
Amount 50mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V1930CAS #:957485-64-2Purity >=98%

Description: FPH2 (also known as BRD-9424) is able to promote differentiation of iPS-derived hepatocytes. In vitro, FPH2 induced functional proliferation of hepatocytes and might be useful for expanding mature human primary hepatocytes. In human primary hepatocytes, FPH2 increased the number of nuclei undergoing mitosis and hepatocyte nuclei count in a concentration dependent way. Also, FPH2 (40 uM) increased the area of hepatocyte colonies with more hepatocytes and Ki67-positive nuclei, which exhibited hepatocyte nuclear morphologies. In primary human hepatocytes from six additional cell sources, FPH2 increased hepatocytes expansion. FPH2 increased hepatocyte at a rate that is consistent with liver regeneration kinetics in vivo.

References: Nat Chem Biol. 2013 Aug; 9(8):514-20.

Molecular Weight (MW)
353.83
Formula
C14H16ClN5O2S
CAS No.
957485-64-2
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 70 mg/mL (197.8 mM)
Water: < 1 mg/mL
Ethanol: < 1 mg/mL
Other info

Chemical Name: 4-[[[(5-chloro-2-methoxyphenyl)amino]thioxomethyl]amino]-1-ethyl-1H-pyrazole-3-carboxamide

InChi Key: PCHRYHSDDPPZBV-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H16ClN5O2S/c1-3-20-7-10(12(19-20)13(16)21)18-14(23)17-9-6-8(15)4-5-11(9)22-2/h4-7H, 3H2, 1-2H3, (H2, 16, 21)(H2, 17, 18, 23)

SMILES Code: O=C(C1=NN(CC)C=C1NC(NC2=CC(Cl)=CC=C2OC)=S)N

Synonyms

FPH2, FPH-2, FPH 2; BRD-9424, BRD9424, BRD 9424

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50mg
Available: In stock
available

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