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pritelivir-mesylate

pritelivir-mesylate

Item no.	V1925-500mg
Manufacturer	InvivoChem LLC
CASRN	1428333-96-3
Amount	500mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1925CAS #:1428333-96-3 Purity >=98% Description: Pritelivir mesylate (formerly known as AIC316 mesylate, BAY 57-1293 mesylate) is a novel and potent helicase primase inhibitor that showed antiviral effect on herpes simplex virus (HSV) with IC50 of 20 nM for both HSV-1 and HSV-2. It represents a new class of potent inhibitors of HSV that target the virus helicase primase complex. BAY 57-1293 exhibits anti-herpes activity through inhibiting the helicase-primase and affecting the viral DNA synthesis. In the in vitro viral replication assay, BAY 57-1293 shows inhibition against HSV-1 F, HSV-2 G and acyclovir-resistant HSV-1 F mutant with IC50 value of 20nM. Thus, BAY 57-1293 has significant potential for the treatment of HSV disease in humans, including those resistant to current medications. References: Nat Med. 2002 Apr; 8(4):392-8; Antimicrob Agents Chemother. 2002 Jun; 46(6):1766-72. Related CAS#:1428333-96-3 (mseylate); 348086-71-5 (free base); 910864-57-2 (HCl); 910864-61-8 (besylate); 2088209-68-9 (sulfate) Related CAS#:1428333-96-3 (mseylate); 348086-71-5 (free base); 910864-57-2 (HCl); 910864-61-8 (besylate); 2088209-68-9 (sulfate)
Molecular Weight (MW)	498.59
Formula	C19H22N4O6S3
CAS No.	1428333-96-3 (mseylate);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 100 mg/mL
	Water: N/A
	Ethanol: N/A
SMILES Code	O=C(N(C)C1=NC(C)=C(S(=O)(N)=O)S1)CC2=CC=C(C3=NC=CC=C3)C=C2.OS(=O)(C)=O
Synonyms	AIC 316 mesylate; AIC-316 mesylate; AIC316 mesylate; BAY57-1293 mesylate; BAY 57-1293 mesylate; BAY-57-1293 mesylate; BAY571293 mesylate; BAY 571293 mesylate; BAY-571293 mesylate; Pritelivir mesylate

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Amount: 500mg

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Delivery expected until 10/4/2024

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