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dihydroergotamine-mesylate

dihydroergotamine-mesylate

Item no.	V18113-1g
Manufacturer	InvivoChem LLC
CASRN	6190-39-2
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V18113CAS #:6190-39-2Purity >=98% Description: Dihydroergotamine Mesylate (DHE; Migranal) is a naturally occuring ergot alkaloid widely used to treat migraines. It has similar actions to the triptans, acting as an agonist to the serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but also interacts centrally with dopamine and adrenergic receptors. References: 1. Colman, I., et al., Parenteral dihydroergotamine for acute migraine headache: asystematic review of the literature. Ann Emerg Med, 2005. 45(4): p.393-401. 2. Saper, J.R., et al., DHE in the pharmacotherapy of migraine: potential for alarger role. Headache, 2006. 46 Suppl 4: p. S212-20. 3. Schaerlinger, B., et al., Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2Creceptors and their possible relevance to antimigraine efficacy. Br JPharmacol, 2003. 140(2): p. 277-84. 4. Menstrual Migraine and Treatment Options: Review. Headache. 2017 Feb; 57(2):194-208.

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