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cemmec13

cemmec13

Manufacturer	InvivoChem LLC
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
Amount	100mg
Item no.	V17878-100mg
CASRN	1790895-25-8
eClass 6.1	32160405
eClass 9.0	32160490
Available
Description	InvivoChem Cat #:V17878CAS #:1790895-25-8Purity >=98% Description: CeMMEC13 is a selective inhibitor of TAF1. CeMMEC13 acts on the bromodomain of TAF1 but does not bind to bromodomains of BRD4, BRD9, or CREBBP. CeMMEC13 synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. References: Sdelci S, Lardeau CH, Tallant C, Klepsch F, Klaiber B, Bennett J, Rathert P, Schuster M, Penz T, Fedorov O, Superti-Furga G, Bock C, Zuber J, Huber KV, Knapp S, Müller S, Kubicek S. Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk. Nat Chem Biol. 2016 Jul; 12(7):504-10. doi:10.1038/nchembio.2080. Epub 2016 May 9. PubMed PMID: 27159579.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100mg

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