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Description: Ramipril (HOE-498) is a potent angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM and with antihypertensive activities. It is quickly hydrolyzed into the active metabolite Ramiprilat. Studies indicate that Ramipril is a more potent inhibitor in comparison to Zofenopril (sc-208496). Acute coronary syndrome investigations demonstrate that Ramipril increases IL-10, and decreases the levels of MCP-1 and IL-18.
References: Circ Res. 2004 Jan 9; 94(1):60-7; Cardiovasc Drugs Ther. 2007 Dec; 21(6):423-9.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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